pentobarbital will lessen the level or effect of nisoldipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.pentobarbital raises effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Warning/Watch. Coadministration of ifosfamide with CYP2B6 inducers may improve metabolism of ifosfamide to its